Attruby (acoramidis) is an oral prescription medicine used to treat heart problems caused by cardiomyopathy from wild-type or hereditary transthyretin-mediated amyloidosis (ATTR-CM). It works by stabilizing transthyretin (TTR) to reduce death and cardiovascular-related hospitalization. Attruby binds to TTR at thyroxine binding sites, slowing the formation of harmful amyloid protein deposits in the heart, which helps slow disease progression.