Hereditary Angioedema HAE
Hereditary angioedema (HAE) is an inherited condition marked by recurrent episodes of non-itchy, non-pitting swelling in areas like the hands, feet, face, tongue, genitalia, and sometimes the larynx or pharynx. The swelling can be life-threatening if it affects the airways, leading to asphyxia. HAE has two main types, both inherited in an autosomal dominant manner: Type I, which accounts for 85% of cases, involves a deficiency of C1 inhibitor, and Type II, responsible for 15% of cases, involves a dysfunctional C1 inhibitor protein.
