Andembry® (garadacimab-gxii)
for Hereditary Angioedema

Andembry (garadacimab-gxii) is used to prevent hereditary angioedema (HAE) attacks in patients 12 and older. It works by inhibiting activated Factor XII (FXIIa), which starts the pathway leading to bradykinin production. By blocking FXIIa, Andembry prevents the activation of kallikrein and reduces bradykinin levels, helping to stop the inflammatory cascade that causes HAE attacks.

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