Auvelity® (dextromethorphan hydrobromide and bupropion hydrochloride)
for Depression/Major Depressive Disorder

Auvelity (dextromethorphan and bupropion) is a rapid-acting antidepressant used to treat Major Depressive Disorder (MDD). It has been shown to improve depression symptoms as early as one week, with continued benefits over time. Auvelity works by increasing glutamate levels in the brain, which may enhance mood and alleviate depressive symptoms, while also affecting norepinephrine and dopamine.

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