Korsuva® (difelikefalin)
for Kidney Disease

Korsuva (difelikefalin) is an injectable synthetic peptide and opioid agonist used to treat pruritus (itchy skin) in adults undergoing hemodialysis for chronic kidney disease (CKD). It activates kappa opioid receptors in the peripheral nervous system, potentially addressing an imbalance in opioid receptor activity linked to pruritus.

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