Mavyret® (glecaprevir and pibrentasvir)
for Hepatitis C

Mavyret is an oral antiviral treatment for chronic hepatitis C virus (HCV) in adults and children aged 3 and older. It contains glecaprevir and pibrentasvir, which work together to block HCV replication. Glecaprevir inhibits the NS3/4A protease needed for viral protein processing, while pibrentasvir blocks the NS5A protein involved in RNA replication. Mavyret treats HCV genotypes 1–6, including certain patients previously treated with other HCV therapies.

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