Tibsovo (ivosidenib) is an oral medication targeting the IDH1 mutation, which can cause blood and bone marrow disorders like acute myeloid leukemia (AML). It is used to treat adults with a confirmed IDH1 mutation in newly diagnosed AML (alone or with azacitidine), relapsed or refractory AML, relapsed or refractory myelodysplastic syndromes, and advanced bile duct cancer (cholangiocarcinoma).