Vyndamax (tafamidis) is an oral prescription medicine used to reduce death or hospitalization related to heart problems in adults with cardiomyopathy from wild-type or hereditary transthyretin-mediated amyloidosis (ATTR-CM). Vyndamax stabilizes abnormal transthyretin, a protein linked to ATTR-CM, preventing harmful amyloid protein deposits in the heart and slowing disease progression.