Xeljanz® (tofacitinib)
for Ulcerative Colitis

Xeljanz (tofacitinib) is an oral JAK inhibitor used to treat conditions like rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis. It works by blocking JAK enzymes (JAK1, JAK2, JAK3, TYK2) inside cells, which are responsible for sending inflammatory signals that trigger cytokine release. By inhibiting these enzymes, Xeljanz reduces the immune system activity, helping to decrease inflammation and symptoms associated with these conditions.

Heart